EOTrol® Selection and Use

Product Availability

EOTrol is currently offered only in the LN formulation (see below), reflecting the concentration of user demand over time into this version.  Inquiries regarding other versions of EOTrol should be addressed to info@targetdiscovery.com.

EOTrol was developed in several formulations that allow the user to select an appropriate EOTrol dynamic coating to optimize their separation outcomes, within the pH and buffer requirements stipulated by the starting mixture.

In addition to being relatively independent of pH and buffer selection, a critical value delivered by EOTrol is the outstanding reproducibility of separation control that it provides for the selected running conditions (note the +/- standard deviation error bars for lot-to-lot variation in the graph below).

Figure. Electroosmotic mobilities (μEOF) measured for several EOTrol dynamic coating
formulations as a function of pH in various CZE buffers. Control EOF measurements
for the buffers alone in bare silica capillary are shown in the black solid circles (note reversal of EOF at
low pH when EOTrol is not present).

EOTrol HN = “High Normal” EOF
(EOF like bare silica capillaries, but without reversal at low pH)

EOTrol LN = “Low Normal” EOF
(EOF like the best coated capillaries, but independent of pH and buffer selection)

EOTrol LR = “Low Reverse” EOF
(EOF like EOTrol LN, but with EOF running in reverse direction)

EOTrol HR = “High Reverse” EOF
(EOF like EOTrol HN, but with EOF running in reverse direction)

The complete EOTrol Product Technical Guide containing detailed information to assist in product selection and in planning optimized separations utilizing EOTrol, is available for your convenience in a downloadable PDF format.

Including the selection guide shown above, the EOTrol Product Technical Guide contains the following sections:

EOTrol Dynamic coatings
EOTrol Properties
Spectral Properties
Capillary Regeneration
Problems Due to Static Coating Non-Uniformity
A Historical Perspective
Reproducibility of Commercial Capillaries with Static Coatings

EOTrol Application Notes

EOTrol Dynamic Coating User Manual

When you are ready to put EOTrol to work in the laboratory, or you are ready to begin designing an SOP for the use of EOTrol, a succinct EOTrol Dynamic Coating User Manual is available for your convenience in a downloadable PDF format.

EOTrol Certificate of Analysis

A certificate of analysis, documenting the internal performance testing results on each lot of EOTrol, is available in a downloadable PDF format at:

EOTrol Safety Data Sheet

One copy of the EOTrol SDS is provided with every shipment of EOTrol. For your convenience, the EOTrol SDS may also be downloaded in PDF format.